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CASP-091A
Caspase 9 Substrate 1, chromogenic
Ac-Leu-Glu-His-Asp-pNA
Size:0.5
P1(RMB):92
MW:674.7
One letter sequence:Ac-LEHD-pNA
Molecular Formula: C29H38N8O11
Description:pNA (4-nitroaniline)-derived caspase substrates widely used for various caspase activities and colorimetric detection. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm. Caspase-9 substrate.\n
Literature Reference:Grutter MG (2000). Curr Opin Struct Biol 10, 649-55; \nGastman BR (2001). Head Neck 23, 409-25; \nGrutter MG (2000). Curr Opin Struct Biol 10, 649-55; \nStennicke HR and Salvesen GS (1999).Cell Death Differ 6, 1054-9; \nStennicke HR and Salvesen GS (1998). Biochim Biophys Acta 1387, 17-31; \nThornberry NA and Lazebnik Y (1998). Science 281, 1312-6; \nTalanian RV, et al. (1997). . J Biol Chem 272, 9677-82;\nFassy F, et al. (1998). Eur J Biochem 253, 76-83; \nDatta R, et al. (1996). Blood 88, 1936-43; \nKoeplinger KA, et al. (2000). Protein Expr Purif 18, 378-87
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