AMYD-110A
Mca-Amyloid b/A4 Protein Precursor770 (667-676)-Lys(DNP)-Arg-Arg amide
Mca-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(DNP)-Arg-Arg-NH2
Size:0.5
P1(RMB):429
MW:2033.2
One letter sequence:Mca-SEVKMDAEFR-K(DNP)-RR-NH2
Molecular Formula:C87H129N27O28S1
Description:Fluorescent peptide substrate that contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. It is used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). Studies reveal that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo.
Literature Reference:H. Koike et al., J. Biochem., 126, 235 (1999)
Cas: