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CASP-057B
Ac-IETD-CHO
Ac-Ile-Glu-Thr-Asp-CHO
Size:5.0
P1(RMB):613
MW:502.5
One letter sequence:Ac-IETD-CHO
Molecular Formula:C21H34N4O10
Description:Peptide aldehyde that corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 172-175). In a concentration range of 0.5 μM, it blocks the formation of the p17 subunit and concomitantly induces the accumulation of the 32kD precursor.
Literature Reference:Z. Han et al, J. Biol Chem., 272, 13422 (1997); M.Garcia-Calvo et al., J. Biol. Chem., 273, 32608 (1998)
Cas:[191338-86-0]