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AMYD-028A
?-Amyloid / A4 Protein Precursor (APP) (96-110), analog
Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2(Cys&Cys bridge)
Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2(Cys&Cys bridge)
Size：0.5
P1(RMB)：337
MW：1918.3
One letter sequence：Ac-NWCKRGRKQCKTHPH-NH2(Cys&Cys bridge)
Molecular Formula：C81H128N32O19S2
Description：Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Literature Reference：D.H. Small et al., J. Neurosci., 14, 2117 (1994)
Cas：
P1(RMB)：337
MW：1918.3
One letter sequence：Ac-NWCKRGRKQCKTHPH-NH2(Cys&Cys bridge)
Molecular Formula：C81H128N32O19S2
Description：Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Literature Reference：D.H. Small et al., J. Neurosci., 14, 2117 (1994)
Cas：
