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SIGN-018
WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist
Trp-Arg-Trp-Trp-Trp-Trp
Size:1
P1(RMB):275
MW:1105.3
One letter sequence:WRWWWW
Molecular Formula:
Description:This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.
Literature Reference:Bae, Y-S. et al. J. Immunol. 173, 607 (2004)
Cas: