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SIGN-009
JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide
Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg
Size:1
P1(RMB):662
MW:2107.4
One letter sequence:CDDYYYGFGCNKFCRPR
Molecular Formula:
Description:This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-κB activation.
Literature Reference:Nickoloff, B. et al. Cell Death Different. 9, 842 (2002).
Cas:
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