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PRPR-001
PrP (106-126)
Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly\nTrifluoroacetate salt
Size:1
P1(RMB):503
MW:1912.3
One letter sequence:KTNMKHMAGAAAAGAVVGGLG
Molecular Formula:C80H138N26O24S2
Description:This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106–126) stimulates leucocyte migration in a dose-dependent manner.
Literature Reference:Diomede, L. et al. Biochem. J. 320, 563 (1996)\nFlorio, T. et al. J. Neurosci. Res. 54, 341 (1998).
Cas:148439-49-0