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CANC-009A
[Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human
Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2
Size:0.25
P1(RMB):542
MW:3582.2
One letter sequence:Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2
Molecular Formula:
Description:This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53.\n
Literature Reference:Krishnan, S. et al. ChemBioChem 12, 254 (2011)\nHuang, J. et al. J Biol Chem 285, 9636 (2010).
Cas:
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