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OPIO-014A
Orphan GPCR SP9155 Agonist P518 (human)\n
Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2\nTrifluoroacetate salt
Size:0.5
P1(RMB):881
MW:2832.17
One letter sequence:TSGPLGNLAEELNGYSRKKGGFSFRF-NH2
Molecular Formula:C127H195N37O37
Description:An RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors. It has been shown to potently activate SP9155 with an EC50 of 7 nM.
Literature Reference:N.Chartrel et al., Proc. Natl. Acad. Sci. USA, 100, 15247 (2003)\nY.Jiang et al., J. Biol. Chem., 278, 27652 (2003)
Cas:600171-68-4