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HIST-014A
[Lys(Ac)12]-Histone H2B (1-22)-GGK(Biotin)-NH2; H2BK12(Ac), biotin-labeled
Pro-Glu-Pro-Ala-Lys-Ser-Ala-Pro-Ala-Pro-Lys-Lys(Ac)-Gly-Ser-Lys-Lys-Ala-Val-Thr-Lys-Ala-Gln-Gly-Gly-Lys(Biotin)-NH2
Size:0.25
P1(RMB):434
MW:2729.3
One letter sequence:PEPAKSAPAPK-K(Ac)-GSKKAVTKAQ-GGK(Biotin)-NH2
Molecular Formula:
Description:This peptide is the fragment of Histone H2B (1-22). It is acetylated at lysine 12 with a C-terminal GG linker followed by a biotinylated lysine. The histone H2B with acetylated at lysine 12 is a target for autoantibodies in systemic lupus erythematosus when it is apoptosis-induced.
Literature Reference:Van Bavel, CC. et al. Mol Immunol 47, 2 (2009).
Cas:N/A