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ADRM-004A
Adrenomedullin (13-52), human
Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2(Cys4&Cys9 bridge)
Size:0.5
P1(RMB):1195
MW:4533.2
One letter sequence:SFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2(Cys4&Cys9 bridge)
Molecular Formula:C200H308N58O59S2
Description:Possessor of vasodilatory activity and proposed modulator of receptor-mediated pulmonary vascular contraction by influence of Ca2+ influx. This fragment has also been suggested to be an endothelium-dependent vasodilator agent in pulmonary vascular bed in rats and a vascular phase modulator in inflammation.
Literature Reference:M. Perret et al., Life Sciences, 53, 377 (1994)
Cas:
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