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CALI-001A
MG-132
Z-Leu-Leu-Leu-CHO
Size:5.0
P1(RMB):276
MW:475.6
One letter sequence:Z-LLL-CHO
Molecular Formula:C26H41N3O5
Description:A potent and reversible cell permeable proteasome inhibitor (Kj 4 nM) of 20S proteasome and calpain. Also shown to initiate neurite outgrouth in PC12 cells with an optimal concentration set at 20 nM.
Literature Reference:D.H. Lee et al., J. Biol. Chem., 271, 27280 (1996);\nK. L. Rock et al, Cell, 78, 761 (1994)
Cas: